Inconsistent detection of an evolving HIV-1 infection by a popular high-throughput screening assay

A 27  year old female patient presented with a 2-week history of sore throat, tender cervical adenopathy, fever and vomiting, following unprotected sex with a new partner. She had also recently developed painful mouth ulcers and a rash. Investigations revealed generalised lymphadenopathy, splenomegaly, an atypical lymphocytosis, transient hepatitis (alanine transferase 86 IU/ml) and thrombocytopaenia (119 × 109/L). Her clinical presentation was consistent with a differential diagnosis of glandular fever, as well as possible HIV seroconversion illness, and an acute viral hepatitis.
Source: Journal of Clinical Virology - Category: Virology Authors: Tags: Letter to the editor Source Type: research