Optimal skin regeneration after full thickness thermal burn injury in the spiny mouse, Acomys cahirinus

The hypertrophic scar which inevitably follows burn injury in mammals consists of a hairless, non-functional epidermis and a linear deposition of collagen in the dermis which lacks the flexibility of normal skin. This represents the greatest unmet challenge in burn recovery and in the human population produces severe problems of pain, stiffness, disabling joint contractures and poor quality of life [1,2].

Source: Burns : Journal of the International Society for Burn Injuries - June 11, 2018 Category: Cosmetic Surgery Authors: Malcolm Maden Source Type: research