Estimating infants' and toddlers' inhalation exposure to fragrance ingredients in baby personal care products.

This study demonstrates an in vitro method for measuring breathing zone air concentrations of fragrances from bath products and lotions. It employed simulated infant bathing and lotion application events and a robot to mimic a toddler's movement within a bathroom setting. The air concentrations in an infant's breathing zone were between <1 and 5 μg/m3 for each of seven common fragrance ingredients, while that in the breathing zone of toddlers in the bathroom was ≤ 1μg/m3. The air concentrations from the bathing additive were linearly related to their Henry's law constants and from the lotion inversely related to their octanol-air coefficients. The proposed approach can help refine risk estimates from inhalation exposure to fragrances used in baby products and guide future risk assessments of new products' safety for their use in baby bath products. PMID: 29877780 [PubMed - as supplied by publisher]
Source: International Journal of Occupational and Environmental Health - Category: Environmental Health Tags: Int J Occup Environ Health Source Type: research