Combined targeted ion channel therapy: can it be an alternative choice for esophageal cancer patients?

Esophageal cancer is a relatively common malignancy with a poor prognosis and is conventionally treated by surgery, chemotherapy, and radiotherapy. However, due to the prevalence of cancer relapse with treatment resistance, novel molecular targets must be identified for the development of alternative therapies. Emerging evidence indicates that ion channels play important roles in cell proliferation, migration, apoptosis and differentitation and could therefore be considered as a potential oncological therapy.
Source: Medical Hypotheses - Category: Biomedical Science Authors: Source Type: research