A molecular epidemiological analysis of tuberculosis trends in South Korea

Molecular epidemiological data are needed to assess tuberculosis (TB)-management policy outcomes in South Korea. IS6110 restriction fragment-length polymorphism (IS6110-RFLP) and mycobacterial interspersed repetitive unit –variable-number tandem repeat (MIRU–VNTR) analyses are major molecular epidemiological tools for investigating the transmission or reactivation of active TB. Here, we determined trends in the clustering rate (i.e., the prevalence of Mycobacterium tuberculosis isolates with identical genotype pa tterns) of active TB and related differences between the 1990s and 2000s in Korea.

Source: Tuberculosis - June 6, 2018 Category: Respiratory Medicine Authors: Kyungjong Kim, Jeong Seong Yang, Hongjo Choi, Heejin Kim, Sang-Hee Park, Se-Mi Jeon, Na-Ra Lim, Changki Kim Source Type: research