Defining the optimal method for reporting prostate cancer grade and tumor extent on magnetic resonance/ultrasound fusion –targeted biopsies

Magnetic resonance (MR)/ultrasound fusion –targeted biopsy (TB) routinely samples multiple cores from each MR lesion of interest. Pathologists can evaluate the extent of cancer involvement and grade using an individual core (IC) or aggregate (AG) method, which could potentially lead to differences in reporting. We reviewed patients who un derwent TB followed by radical prostatectomy (RP). TB cores were evaluated for grade and tumor extent by 2 methods. In the IC method, the grade for each TB lesion was based on the core with the highest Gleason score.

Source: Human Pathology - March 15, 2018 Category: Pathology Authors: Jennifer B. Gordetsky, Luciana Schultz, Kristin K. Porter, Jeffrey W. Nix, John V. Thomas, Maria del Carmen Rodriguez Pena, Soroush Rais-Bahrami Tags: Original contribution Source Type: research