Erroneous Thyroid Diagnosis Due to Over-the-counter Biotin

Biotin is commonly used in immunoassays to measure several hormones and non-hormone analytes, including thyroxine (T4), thyrotropin (TSH), parathyroid hormone, and ferritin [1]. Cases of thyroid function test assay interference have been documented in patients taking high doses of biotin for the treatment of inborn errors of metabolism and progressive multiple sclerosis; euthyroid patients appeared hyperthyroid and a newborn baby with hypothyroidism was misdiagnosed due to the spurious lowering of TSH [2 –4].
Source: Nutrition - Category: Nutrition Authors: Tags: International Ward Rounds Source Type: research