A Nomogram based prognostic score that is superior to conventional TNM staging in predicting outcome of surgically treated T4 buccal mucosa cancer: Time to think beyond TNM

TNM staging system since 1953, when it was first proposed by French surgeon, Denoix [1,2], to Union for International Cancer Control (UICC) for staging and prognostication of solid tumors, has fulfilled its original mandate remarkably. Initially, based on the simple theory that outcomes worsened as the tumor progressed from the primary site (T) to regional lymph nodes (N) and then to distant organs (M), TNM system has evolved over the years [2]. The American joint committee on cancer (AJCC) and UICC versions of the TNM system were unified in 1987 and since then through continuous collaboration these organizations have maintained a liaison to ensure compatibility of subsequent revised staging classifications.

Source: Oral Oncology - April 10, 2018 Category: Cancer & Oncology Authors: Saurabh Bobdey, Manish Mair, Sudhir Nair, Deepa Nair, Ganesh Balasubramaniam, Pankaj Chaturvedi Source Type: research