A clinical prognostic model compared to the newly adopted UICC staging in an independent validation cohort of P16 negative/positive head and neck cancer patients

Various treatment approaches are available for patients with non-metastatic head and neck squamous cell carcinoma (HNSCC) including radiation as monotherapy or in combination with systemic therapy and/or surgery. Currently, several trials testing treatment de-intensification in low risk patients are in progress [1] and a few phase I trials testing treatment intensification in patients with assumed high risk of recurrence has been conducted [2 –4]. In both cases, it is important to select the appropriate study population for each trial.

Source: Oral Oncology - April 17, 2018 Category: Cancer & Oncology Authors: Jacob H. Rasmussen, Katrin H åkansson, Gregers B. Rasmussen, Ivan R. Vogelius, Jeppe Friborg, Barbara M. Fischer, Søren M. Bentzen, Lena Specht Source Type: research