Predictors of oropharyngeal cancer survival in Europe

Cancers arising in the oral cavity and pharynx have an estimated global burden of 442,760 incident cases and 241,458 deaths each year [1]. Tobacco smoking and alcohol consumption explain nearly 70% of these cancers [2,3]. Infection by Human PapillomaVirus (HPV), specifically type 16 (HPV16) causes a subset of cancers, particularly those arising at the tonsil, oropharynx, soft palate and base of the tongue (collectively referred to as oropharyngeal cancers-OPC) [4]. Further, HPV16-positive (HPV16+) OPC is described to be epidemiologically, molecularly and clinically distinct from HPV16-negative (HPV16-) OPC [5].

Source: Oral Oncology - May 2, 2018 Category: Cancer & Oncology Authors: D. Anantharaman, A. Billot, T. Waterboer, T. Gheit, B. Abedi-Ardekani, P. Lagiou, A. Lagiou, W. Ahrens, I. Holc átová, F. Merletti, K. Kjaerheim, J. Polesel, L. Simonato, L. Alemany, M. Mena Cervigon, T.V. Macfarlane, A. Znaor, P.J. Thomson, M. Robinson Source Type: research