Randomized clinical trial exploring the optimal duration of antimicrobial prophylaxis in patients undergoing pancreaticoduodenectomy following biliary drainage

Objectives The aim of this dual-center randomized controlled trial was to determine the optimal duration of antimicrobial prophylaxis in patients treated with pancreaticoduodenectomy (PD) who underwent preoperative biliary drainage (PBD) but were without cholangitis. Some reports revealed that PBD in patients undergoing pancreatectomy increased the rate of peri-operative complications. However, no clinical trial has evaluated the optimal duration of antimicrobial prophylaxis with a focus on patients who underwent PD following PBD.

Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Sohei Satoi, Yomohisa Yamamoto, Tsutomu Fujii, Suguru Yamada, Hiroaki Yanagimoto, So Yamaki, Hideki Takami, Satoshi Hirooka, Hisashi Kosaka, Masaya Kotsuka, Yasuhiro Kodera Tags: Session 4. Surgical issues of pancreatic tumor resection - free papers Source Type: research