Novel pancreatic cancer susceptibility loci discovered through genome-wide association studies

Objectives Genome-wide association studies (GWAS) have identified several regions convincingly or suggestively associated with pancreatic cancer risk. However, estimates of heritability suggest that a large number of loci remain to be discovered. To identify additional susceptibility loci, the PANcreatic Disease ReseArch (PANDoRA) consortium participated in additional GWAS, in collaboration with USA-based consortia, namely PanScan3 and PanC4.

Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Federico Canzian, Daniele Campa, Ofure Obazee, Cosmeri Rizzato, Maria Gazouli, Giulia Martina Cavestro, Aldo Scarpa, Stefania Moz, Raffaele Pezzilli, Andrea Mambrini, Ugo Boggi, Gabriele Capurso, Livia Archibugi, Franco Bambi, Angelo Andriulli, Pavel Souc Tags: Session 5. Pancreatic Cancer: predispositions and diagnostic advances - free papers Source Type: research