Genetic knockout of SARI does not affect the severity of caerulein-induced acute pancreatitis in mice

Objectives SARI (suppressor of activator protein-1, regulated by interferon) is a novel gene with anti-inflammatory and tumour suppressive effects. SARI expression occurs in diverse tissues, highest in the pancreas. We sought to assess the role of SARI in experimental acute pancreatitis (EAP). To investigate the effect of SARI knockout (SARI-/-) on the severity of EAP.

Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Chenxia Han, Lei Dai, Shi Na, Tingting Liu, Xiaoying Zhang, Robert Sutton, Wei Huang, Hongxin Deng, Qing Xia Tags: 3. Experimental Pancreatitis I Source Type: research