Dimethyl trisulfide: A promising drug candidate in experimental acute pancreatitis

Objectives The pathogenesis of acute pancreatitis (AP) is not well understood and the disease has no specific therapy. Previous investigations have demonstrated that hydrogen sulfide (H2S) and organic trisulfides are biologically active and have anti-inflammatory properties. Dimethyl trisulfide (DMTS) is an organic trisulfide found in some vegetables which also has analgesic effects. Our aim was to investigate whether DMTS could alleviate the severity of experimental AP.

Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: L óránd Kiss, Gabriella Fűr, Ahmad Totunji, Richárd Pető, Zsolt Balla, Emese Réka Bálint, Petra Pallagi, József Maléth, Viktória Venglovecz, Péter Hegyi, Zoltán Rakonczay Tags: 3. Experimental Pancreatitis I Source Type: research