Diagnostic criteria for acute pancreatitis should be reconsidered in patients with diabetes mellitus

Objectives The incidence of both acute pancreatitis (AP) and diabetes mellitus (DM) have been increasing, therefore, more and more AP patients have also been suffering from DM. Basic research revealed that the pancreatic enzyme synthesis is non-parallel in acinar cells. A strong reduction in amylase and elevation of trypsin synthesis are observed in diabetic animals. Our aim was to i) analyze the amylase level on-admission in AP and ii) to understand the effect of DM on the course and outcome of AP in prospectively collected, large, multicentre cohort.

Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Klaudia K árász, Bálint Erőss, Mária Papp, Péter Mátrai, Katalin Márta, Dániel Pécsi, Dóra Illés, Czimmer József, Eszter Fehér, Erika Darvasi, Zoltán Szepes, Tamás Takács, Patrícia Sarlós, József Hamvas, László Gajdán, Ferenc Izbék Tags: 5. Diabetes and the pancreas Source Type: research