Tumor regression grade (TRG) evaluation of 29 borderline/locally advanced pancreatic cancers (LAPCs) after neoadjuvant chemotherapy (NACT) using different pathological scores: a clinical and prognostic correlation

Objectives Only 20-30% of patients with pancreatic cancer (PC) are candidate for surgery at diagnosis. In LAPC resectability can be achieved in a small proportion of patients after chemotherapy and chemoradiotherapy. Pathology report has an essential role in assessing the efficacy of therapy and the completeness of surgery. Determining the TRG in patients with PC is challenging. Numerous TRG scores are currently used without a general agreement on the most reliable and almost all data available regard patients treated with both chemo and radiotherapy.
Source: Pancreatology - Category: Gastroenterology Authors: Tags: 8. Pancreatic Cancer I Source Type: research