Pancreatic cancer cells enrich phospho-paxillin in their filopodia during neural invasion

Objectives Neural invasion (NI) is a leading cause of local recurrence, neuropathic pain sensation in pancreatic ductal adenocarcinoma (PDAC) and is encountered in up to 100% of PDAC cases. The changes that occur in the cytoskeleton of neuro-invasive PDAC cells has, however, never been analyzed.

Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Xiaobo Wang, Steffen Teller, Ihsan Ekin Demir, Helmut Friess, G üralp O. Ceyhan Tags: 9. Experimental pancreatic cancer I Source Type: research