Pancreatic stellate cells augment neural invasion in pancreatic cancer

Objectives Neural invasion is one of most unfavorable prognostic factors in pancreatic cancer (PCa). Neural invasion in PCa is particularly frequent in desmoplastic tissue areas. Pancreatic stellate cells (PSC) emerged in recent years as the main actor for the generation of pancreatic fibrosis in PCa. Thus, here, we investigated whether pancreatic stellate cells (PSC) can augment neural invasion in PCa.

Source: Pancreatology - June 1, 2018 Category: Gastroenterology Authors: Xiaobo Wang, Steffen Teller, Ihsan Ekin Demir, Helmut Friess, G üralp O. Ceyhan Tags: 9. Experimental pancreatic cancer I Source Type: research