Towards earlier detection of PDAC: Validation of a biomarker panel for the identification of type 3c diabetes among individuals newly diagnosed with type 2 diabetes
Objectives At the time of diagnosis over 40% of PDAC patients have diabetes mellitus (DM); up to 80% have glucose intolerance. The relationship between PDAC and DM is complex. Long-standing DM (LSDM) increases the risk of PDAC by approximately twofold. However, epidemiological data indicate that PDAC can cause DM, with DM diagnosis preceding cancer diagnosis by up to 3 years. In ∼50% of PDAC cases DM is of recent onset, making individuals with new-onset DM the largest high-risk group for PDAC.
Source: Pancreatology - Category: Gastroenterology Authors: Lucy Oldfield, Rohith Rao, Tejpal Purewal, John P. Neoptolemos, William Greenhalf, Christopher Halloran, Eithne Costello Tags: 9. Experimental pancreatic cancer I Source Type: research
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