Influences of intrauterine semen administration on regulatory T lymphocytes in the oestrous mare (Equus caballus)

In the mare, early pregnancy loss is common, but involvement of the maternal immune system in the pathogenesis of this condition has not been investigated in detail so far. In the present study, we assessed effects of exposure of the endometrium to semen or seminal plasma in oestrous mares on the response of regulatory T lymphocytes (Tregs) in the peripheral circulation as well as in the endometrium. Raw semen, seminal plasma or PBS (control) were introduced into the uterus of oestrous mares (n=12).

Source: Theriogenology - June 1, 2018 Category: Genetics & Stem Cells Authors: Constanze Hartmann, Wilhelm Gerner, Ingrid Walter, Armin Saalm üller, Christine Aurich Source Type: research