Clonal transmission of NDM-5-producing Escherichia coli belonging to high-risk sequence type ST405
Carbapenemase-producing Enterobacteriaceae are a critical public-health problem. The European Survey on Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) reported that 19% of carbapenem-non-susceptible Escherichia coli isolates produced carbapenemases [1]. In Spain, an upward trend in carbapenemase-producing E. coli has been observed, mainly due to the dissemination of OXA-48 [2]; however, sporadic occurrence of NDM-producers has been reported [2,3]. The success of high-risk E. coli clones might be due to factors such as increased transmission and colonisation capacity, antibiotic multiresistance and enhanced virulence.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Laura Barrado, Mar ía Pérez-Vázquez, José Luis del Pozo, Carmen Martín-Salas, José Leiva, Ana Mazón, Carmen Ezpeleta, Jesús Oteo Tags: Letter to the Editor Source Type: research