Statistical testing and power analysis for brain-wide association study

The human brain connectome is usually modeled as a network. In the brain ’s network, accurately locating the connectivity variations associated with phenotypes, such as clinical symptoms, is critical for neuroscientists. With the development of neuroimaging technology and an increasing number of publicly available datasets, such as the 1000 Functional Connectomes Proje ct (FCP) (Biswal et al., 2010), Human Connectome Project (HCP) (Glasser et al., 2016) and UK-Biobank (Miller et al., 2016), large-scale, image-based association studies have become possible and should help us improve our understanding of human brain functions.

Source: Medical Image Analysis - April 4, 2018 Category: Radiology Authors: Weikang Gong, Lin Wan, Wenlian Lu, Liang Ma, Fan Cheng, Wei Cheng, Stefan Gr ünewald, Jianfeng Feng Source Type: research