Magnetic resonance imaging based assessment of bone microstructure as a non-invasive alternative to histomorphometry in patients with chronic kidney disease

Chronic kidney disease (CKD) adversely affects bone microarchitecture and increases fracture risk. Historically, bone biopsy has been the ‘gold standard’ for evaluating renal bone disease but is invasive and infrequently performed. High-resolution magnetic resonance imaging (MRI) quantifies bone microarchitecture noninvasively. In patients with CKD, it has not been compared with results derived from bone biopsy or with imaging usi ng dual energy X-ray absorptiometry (DXA).

Source: Bone - May 31, 2018 Category: Orthopaedics Authors: Ashish K. Sharma, Nigel D. Toussaint, Grahame J. Elder, Rosemary Masterson, Stephen G. Holt, Patricia L. Robertson, Peter R. Ebeling, Paul Baldock, Rhiannon C. Miller, Chamith S. Rajapakse Tags: Full Length Article Source Type: research