A Pilot Study of GABAB Correlates with Resting-State Functional Connectivity in Five Depressed Female Adolescents

Major depressive disorder (MDD) is diagnosed clinically using functional and mood-related impairments that are suggestive of but not specific to underlying neuropathology. There is significant variation in the etiology of MDD and in the response to treatment between patients (Kupfer et al., 2012). Rapidly implementable biomarkers are needed to characterize patient phenotypes and inform treatment plans. This is especially true for adolescents, in whom disease processes and neuromodulatory treatments interact with the developing brain.
Source: Psychiatry Research: Neuroimaging - Category: Psychiatry Authors: Tags: Short Communication Source Type: research