Gabapentin reverses central hypersensitivity and suppresses medial prefrontal cortical glucose metabolism in rats with neuropathic pain
Conclusions:
Our results indicate that GBP analgesic effect may be mediated by reversing central hypersensitivity, and suppressing mPFC, a crucial part of the cortical representation of pain, in the brain.
Source: Molecular Pain - Category: Molecular Biology Authors: Hsiao-Chun LinYu-Hsin HuangTzu-Hao ChaoWen-Ying LinWei-Zen SunChen-Tung Yen Source Type: research
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