Radiofrequency ablation for Barrett's esophagus related neoplasia.

Radiofrequency ablation for Barrett's esophagus related neoplasia. Minerva Chir. 2018 May 25;: Authors: Krajciova J, Vackova Z, Spicak J, Martinek J Abstract Barrett's esophagus (BE) is a premalignant condition associated with increased risk of developing esophageal adenocarcinoma. In the past, BE patients with high-grade intraepithelial neoplasia (IEN) or early adenocarcinoma (EAC) were indicated for esophagectomy. With the recent advance in endoscopy, endoscopic techniques have surpassed esophagectomy in the treatment of Barrett's esophagus related neoplasia (BORN) and minimized the treatment-related morbidity. Patients with IEN are candidates for endoscopic treatment - endoscopic mucosal resection (ER) of visible lesions and/or ablation therapy of flat Barrett's mucosa. ER combined with radiofrequency ablation (RFA) is now considered as a gold standard for treatment of patients with early Barrett's cancer. RFA is currently the most effective method of ablation used in the treatment of LGIN/HGIN without visible lesions and for ablation of residual Barrett's mucosa following ER/ESD of EAC or HGIN aiming to achieve complete eradication of Barrett's surface and thus, decreasing the risk of recurrent dysplasia or cancer. The rates of complete remission of neoplasia (CR-N) and metaplasia (CR-M) after completion of endoscopic treatment are 81-92.6% and 75- 88.2%, respectively. The aim of this article is to review the principles, techniqu...
Source: Minerva Chirurgica - Category: Surgery Tags: Minerva Chir Source Type: research