sjTREC quantification using SYBR quantitative PCR for age estimation of bloodstains in a Japanese population

In forensic investigations, DNA genotyping is widely used for individual identification and paternity testing. Moreover, DNA phenotyping has practical applications such as age estimation [1]. Individual age is a useful phenotypic trait for identification purposes. Previously proposed genetic indicators for human age estimation are based on the accumulation of mitochondrial DNA deletions [2,3] and telomere shortening [4,5]. These are not suitable for practical applications because of the complex procedures and problems with accuracy.

Source: Legal Medicine - March 15, 2018 Category: Forensic Medicine Authors: Eisuke Yamanoi, Saori Uchiyama, Makoto Sakurada, Yasuhiro Ueno Source Type: research