Altered maternal and placental lipid metabolism and fetal fat development in obesity: Current knowledge and advances in non-invasive assessment
Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated with pregnancy complications such as preeclampsia and gestational diabetes, and offspring long-term metabolic health is impacted as the consequence of altered fetal growth, physiology and often iatrogenic prematurity. The metabolic changes associated with maternal obesity and/or the consumption of a high-fat diet effecting maternal lipid profiles and metabolism have also been documented to specifically affect placental function and may underlie changes in fetal development and life course disease risk.
Source: Placenta - Category: Reproduction Medicine Authors: Flavien Delhaes, Stephanie A. Giza, Tianna Koreman, Genevieve Eastabrook, Charles A. McKenzie, Samantha Bedell, Timothy R.H. Regnault, Barbra de Vrijer Source Type: research
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