Targeting protein kinase C: A novel paradigm for heart failure therapy

Heart failure continues to be a disease associated with significant morbidity and mortality in both children and adults. Guidelines exist for the recommended management of heart failure in both populations. Many of these therapies are targeted at the neurohormonal response that occurs in heart failure. Although recent additions have been made to the guidelines for the use of novel oral therapies in heart failure, the impact of these therapies in real-world practice remains to be seen. There are additional targets in heart failure that have been unexplored in clinical studies.

Source: Progress in Pediatric Cardiology - May 23, 2018 Category: Cardiology Authors: John Lynn Jefferies Tags: Review Source Type: research