An Ultra-Sensitive Abbott ARCHITECT ® Assay for the Detection of Hepatitis B Virus Surface Antigen (HBsAg)

In 2017, the global prevalence of HBV infection in the general population was 3.5% with an estimated 257 million persons were infected, leading to over 880,000 deaths [1]. The most important serological marker of HBV infection is Hepatitis B virus surface antigen (HBsAg) [2]. An individual is likely infectious when HBsAg is present, and antigen concentration roughly correlates with infection level and disease severity [3]. Infection can also be detected by ultra-sensitive nucleic acid amplification techniques (NAT) for HBV DNA [4].
Source: Journal of Clinical Virology - Category: Virology Authors: Source Type: research