The effects of platelet rich plasma on healing of full thickness burns in swine
Platelet-rich plasma (PRP) is the plasma fraction of autologous blood in which the platelet concentration is considerably higher than in whole blood due to processing and concentration [1]. Activated platelets release key wound healing factors including platelet-derived growth factor (PDGF), transforming growth factor beta (TGF- β), vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), and epidermal growth factor [1,2]. By delivering supra-physiological concentrations of a variety of growth factors and cytokines these preparations are used to enhance wound healing in bone and soft tissue injuries.
Source: Burns : Journal of the International Society for Burn Injuries - Category: Cosmetic Surgery Authors: Adam J. Singer, Jimmy Toussaint, Won Taek Chung, Steve McClain, Vivek Raut, Lior Rosenberg Source Type: research