Epidemiological cut-off values to separate wildtype from non-wildtype Campylobacter fetus to ciprofloxacin

The aim of the present study was to propose epidemiological cut-offs that could be used in routine practice to separate wildtype from non-wildtype Campylobacter fetus to ciprofloxacin. A total of 123 Campylobacter fetus isolates obtained from human samples were used for this purpose. Based on the determination of inhibition zone diameter, minimum inhibitory concentration (MIC) and sequencing of the quinolone resistance determining region in the gyraseA gene, for all tested isolates, the following cut-offs were proposed: ciprofloxacin-wildtype if inhibition zone diameter ≥22mm or MIC ≤0.5 mg/L.

Source: Diagnostic Microbiology and Infectious Disease - May 18, 2018 Category: Microbiology Authors: L B énéjat, E Sifré, C Domingues Martins, A Ducournau, A Buissonnière, E Bessède, F Mégraud, P Lehours Source Type: research