Disease caused by non-tuberculous mycobacteria in children with cystic fibrosis

Non-tuberculous mycobacterial (NTM) (especially M. abscessus complex) infections pose a considerable challenge in the management of lung disease in patients with cystic fibrosis (CF). The apparent increase in prevalence is likely multifactorial. Emergent evidence of patient-to-patient transmission and isolation of highly resistant strains is concerning for all CF centers around the world. Treatment is often long and burdensome with multiple agents. Treatment side effects are frequent and can cause significant morbidity.

Source: Paediatric Respiratory Reviews - May 18, 2018 Category: Respiratory Medicine Authors: Mimi Lu, Vishal Saddi, Philip N. Britton, Hiran Selvadurai, Paul Robinson, Chetan Pandit, Ben J. Marais, Dominic A. Fitzgerald Source Type: research