Reverse line probe assay for cheap detection of Single Nucleotide Polymorphisms in Mycobacterium tuberculosis

This study presents a low-cost reverse hybridization line probe technique for detecting SNPs in Mycobacterium tuberculosis. The proposed test is able to detect mutations in the RRDR of rpoB gene in M. tuberculosis with specificity and sensitivity of 98% and 100%, respectively and for an average cost of less than €3 per sample.

Source: Tuberculosis - March 26, 2018 Category: Respiratory Medicine Authors: Memona Yasmin, Guislaine Refregier, Rubina Tabassum Siddiqui, Rizwan Iqbal, Shahid Ahmad Abbasi, Sabira Tahseen Tags: Diagnostics Source Type: research