Identification of TB-E12 as a novel FtsZ inhibitor with anti-tuberculosis activity

In this study, we used phenotype screening of M. smegmatis and model screening targeting M. tuberculosis FtsZ (Mtb-FtsZ) to identify a hit compound TB-E12.

Source: Tuberculosis - April 5, 2018 Category: Respiratory Medicine Authors: Yuan Lin, Hongjuan Zhang, Ningyu Zhu, Xia Wang, Yanxing Han, Minghua Chen, Jiandong Jiang, Shuyi Si Source Type: research