Detection of colistin-resistant gram-negative rods by using the Superpolymyxin medium

The commercial SuperPolymyxin medium (ELITechGroup, Puteaux, France), currently licensed in Europe, is aimed to screen for either intrinsic or acquired colistin resistance in Gram negatives. It was tested for screening colistin-resistant Gram negative rods from bacterial cultures of 145 colistin-resistant and 86 colistin-susceptible Gram negative rods isolates. It exhibited a sensitivity and specificity of 95.2% (138/145) and 95.3% (82/86), respectively. The sensitivity for the detection of the 25 isolates carrying plasmid-mediated colistin resistance genes (mcr-1, mcr-2, mcr-3, and mcr-4) from bacterial cultures was of 100%.
Source: Diagnostic Microbiology and Infectious Disease - Category: Microbiology Authors: Source Type: research