Complex networks reveal early MRI markers of Parkinson ’s disease

Parkinson ’s disease (PD) is a heterogeneous progressive neurological disorder, firstly described almost two centuries ago, basically related with early death of dopaminergic neurons in the substantia nigra and characterized by both motor and non-motor features (Gibb and Lees, 1988; Jankovic, 2008). It is r ecognized that age is the greatest risk factor for PD, its incidence reaches a maximum at about 80 years of age, thus the rising life expectancy is expected to increase the number of patients at more than 30% by 2030 (Dorsey et al., 2007).
Source: Medical Image Analysis - Category: Radiology Authors: Source Type: research