Subtle behavioural responses during negative emotion reactivity and down-regulation in bipolar disorder: A facial expression and eye-tracking study

Bipolar disorder (BD) is a chronic psychiatric disorder characterised by recurrent affective episodes of mania and depression and high rates of misdiagnosis (Goodwin  and Jamison, 2007). Difficulty with emotion regulation is a key feature of BD that contributes to poor psychosocial outcomes and occupational functioning (Aparicio et al., 2017; Van Rheenen and Rossell, 2014). The genetic origins of BD is still unclear, partly due to patho-etiological heterogene ity (Kerner, 2015) and complex gene-environment interactions (Uher, 2014), and thus the pathophysiology of the illness remains elusive (Miskowiak et al., 2016).

Source: Psychiatry Research - May 17, 2018 Category: Psychiatry Authors: Ingrid Broch-Due, Hanne Lie Kj ærstad, Lars Vedel Kessing, Kamilla Miskowiak Source Type: research