Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion: A Post Hoc Analysis of the PROTECT Data [Original Articles]

Conclusions:
In patients admitted for acute heart failure, WRF defined as a creatinine increase of ≥0.3 mg/dL was associated with longer length of hospital stay, and worse 30- and 90-day outcomes. However, effects were largely driven by patients who had residual congestion at the time of renal function assessment.

Clinical Trial Registration
: URL: https://www.clinicaltrials.gov. Unique identifiers: NCT00328692 and NCT00354458.

Source: Circulation: Heart Failure - May 10, 2018 Category: Cardiology Authors: Metra, M., Cotter, G., Senger, S., Edwards, C., Cleland, J. G., Ponikowski, P., Cursack, G. C., Milo, O., Teerlink, J. R., Givertz, M. M., OConnor, C. M., Dittrich, H. C., Bloomfield, D. M., Voors, A. A., Davison, B. A. Tags: Heart Failure Original Articles Source Type: research