A Case of Primary Squamous Cell Carcinoma of the Breast with Pathologic Complete Response After Neoadjuvant Chemotherapy

Primary squamous cell carcinoma (SCC) of the breast is a metaplastic carcinoma subtype which includes fibromatosis-like and sarcomatoid features.1 Etiology and pathogenesis of primary SCC of breast still remains unclear. This is a very aggressive tumor with poor prognosis and is seen less than 0.1% (0.04% to 0.075%) of all breast malignancies.2 Other sites of primary SCC should be ruled out first to classify these tumors as primary SCC of the breast. Here we present a case of locally advanced primary SCC of the breast.

Source: Current Problems in Cancer - May 8, 2018 Category: Cancer & Oncology Authors: Ozkan ALAN, Tugba Akin TELLI, Ozlem ERCELEP, Rahib HASANOV, Eda Tanrikulu SIMSEK, Aydan MUTIS, Tunc ONES, Handan KAYA, Perran Fulden YUMUK Source Type: research