Small cell carcinoma of the urinary bladder: a Clinicopathologic and Immunohistochemical analysis of 81 cases

Small cell carcinoma (SmCC) of the bladder is a rare disease. We retrospectively studied a large series of bladder SmCC from a single institution. The patients included 69 men and 12 women with a mean age of 68years. Most bladder SmCC were presented at advanced stage with tumors invading the muscularis propria and beyond (n=77). SmCC was pure in 27 cases and mixed with other histologic types in 54 cases, including urothelial carcinoma (UC) (n=32), UC in situ (n=26), glandular (n=14), micropapillary (n=4), sarcomatoid (n=4), and squamous (n=3), and plasmacytoid (n=1) features.

Source: Human Pathology - May 12, 2018 Category: Pathology Authors: Gang Wang, Li Xiao, Miao Zhang, Ashish M. Kamat, Arlene Siefker-Radtke, Colin P. Dinney, Bogdan Czerniak, Charles C. Guo Tags: Original Contributions Source Type: research