Common Coding Variants in SCN10A Are Associated With the Nav1.8 Late Current and Cardiac Conduction [Original Articles]

Conclusions:
Our findings suggest an association between genetic variation in SCN10A, the late sodium current, and alterations in cardiac conduction.

Source: Circulation: Cardiovascular Genetics - May 11, 2018 Category: Cardiology Authors: Macri, V., Brody, J. A., Arking, D. E., Hucker, W. J., Yin, X., Lin, H., Mills, R. W., Sinner, M. F., Lubitz, S. A., Liu, C.-T., Morrison, A. C., Alonso, A., Li, N., Fedorov, V. V., Janssen, P. M., Bis, J. C., Heckbert, S. R., Dolmatova, E. V., Lumley, T. Tags: Electrophysiology, Atrial Fibrillation, Ion Channels/Membrane Transport, Functional Genomics Original Articles Source Type: research