Lipid mediator Leukotriene D4-induces airway epithelial cells proliferation through EGFR/ERK1/2 pathway

Conclusion In conclusion, these results suggest that sustained presence of lipid inflammatory mediator LTD4 could induce human airway epithelial cell proliferation through ERK1/2 phosphorylation, either directly via CysLT1 receptor or by transactivating EGFR. Graphical abstract

Source: Prostaglandins and Other Lipid Mediators - May 8, 2018 Category: Lipidology Source Type: research