Managing wounds with exposed bone and tendon with an esterified hyaluronic acid matrix (eHAM): a literature review and personal experience.

The loss of extracellular matrix in combination with the exposure of structures such as bone and tendon pose a major challenge; the development of granulation tissue and subsequent reepithelialization over these structures is extremely slow and often may not happen at all. Replacement of the matrix has been shown to significantly increase the chances of healing since, with revascularization of the matrix, a wound bed is created that may either heal by secondary intention or via the application of a skin graft.

Source: Journal of the American College of Certified Wound Specialists - May 7, 2018 Category: Dermatology Authors: Richard Simman, Michel H.E. Hermans Source Type: research