Age-related changes in female mouse cortical bone microporosity

Osteocyte lacunae are small cavities within the bone matrix. Their dimensions and spatial arrangement affect bone mechanical properties. Furthermore, their size and shape affect the strain in bone tissue close to the lacunae; hence, they are supposed to affect the mechanosensory function of the osteocytes residing in the lacunae. It was the purpose of this study to quantify the morphological features of osteocyte lacunae, whether these are affected by aging and whether these vary among different anatomical location.

Source: Bone - May 5, 2018 Category: Orthopaedics Authors: Haniyeh Hemmatian, Micha ël R. Laurent, Astrid D. Bakker, Dirk Vanderschueren, Jenneke Klein-Nulend, G. Harry van Lenthe Tags: Full Length Article Source Type: research