Prevalence of Antiphospholipid Antibody Positivity and Association of Pretransplant Lupus Anticoagulant Positivity With Early Allograft Dysfunction in Liver Transplantation

Antiphospholipid antibodies (aPL), including anticardiolipin (aCL), anti- β2-glycoprotein I (anti-β2GPI), and lupus anticoagulant (LA) antibodies, are frequently found in liver cirrhosis and associated with splanchnic vein thrombosis. Although the risk factors of early allograft dysfunction (EAD) are known, the association between EAD and aPL has been poorly investigate d. We hypothesized that LA, potent aPL with thrombotic potential, may be associated with EAD development after living donor liver transplantation (LDLT).

Source: Transplantation Proceedings - May 1, 2018 Category: Transplant Surgery Authors: H.-M. Kwon, K.-W. Jung, Y.-J. Moon, H.-W. Jung, Y.-S. Park, I.-G. Jun, J.-G. Song, G.-S. Hwang Tags: Asian Transplantation Week 2017 Source Type: research