Efficient isolation and high yield of epidermal cells from foreskin biopsies by dynamic trypsinization

Skin is an essential barrier that protects organisms from the environment and is composed of epidermis, dermis and subcutaneous tissue [1]. Most cells in the epidermis are keratinocytes, which constitute 90% of the cell population in this layer [2]. Keratinocyte progenitor cells at the epidermal-dermal junction are essential for regenerating and maintaining the normal structure and function of the epidermis. Frequently, epidermal cells must be isolated and cultivated for scientific studies or clinical applications for wound care.
Source: Burns : Journal of the International Society for Burn Injuries - Category: Cosmetic Surgery Authors: Source Type: research