Development of a contaminated ischemic porcine wound model and the evaluation of bromelain based enzymatic debridement

Chronic wounds, such as venous, arterial and diabetic ulcers, affect an estimated 7 million patients in the U.S. alone each year, with costs exceeding $25 billion annually [1]. While multiple topical therapies have been evaluated, few have shown significant benefit in healing chronic wounds. However, a cornerstone of wound therapy is wound debridement [2], whereby necrotic, and often contaminated tissue is removed by means of autolytic, enzymatic, or surgical debridement.

Source: Burns : Journal of the International Society for Burn Injuries - April 13, 2018 Category: Cosmetic Surgery Authors: Adam J. Singer, Jimmy Toussaint, Won Taek Chung, Steve A. McClain, Richard A.F. Clark, Eilon Asculai, Dafna Geblinger, Lior Rosenberg Source Type: research