Effect of skin graft thickness on scar development in a porcine burn model

Hypertrophic scarring is a common complication following burn injury, with reported incidence rates ranging from 30 –75% [1]. The scars are associated with pain, pruritus, erythema, and stiffness [2]. In addition, contractures due to hypertrophic scarring can lead to significant deformities and result in loss of function of the affected limb or joint [3]. Although there is a range of treatment options available including pressure garments [4,5], silicone gels [6,7], corticosteroid injections [8], and laser treatment [9,10], none of these therapies has been able to completely prevent or cure hypertrophic scarring.
Source: Burns : Journal of the International Society for Burn Injuries - Category: Cosmetic Surgery Authors: Source Type: research