CTCF knockout reveals an essential role for this protein during the zebrafish development

In conclusion, CTCF is a ubiquitous factor during the zebrafish development, which regulates the correct formation of different structures of the embryo, and its deregulation impacts on essential cell survival genes. Overall, this work provides a basis to look for the particular functions of CTCF in the different developing tissues and organs of the zebrafish.

Source: Mechanisms of Development - May 1, 2018 Category: Biology Source Type: research